Dr. Deanna Church is currently the Senior Director of Applications at 10x Genomics. In this role, she leads a diverse group of scientists who are developing approaches for improved genome analysis, using Linked-Reads, as well as expanding the application space of single cell transcriptome profiling. Previously, she was Senior Director of Genomics and Content at Personalis, where she helped advance the field of genomics based clinical diagnostics. Prior to that, she was a staff scientist at NCBI, where she oversaw several projects concerning managing and displaying genomic data, including dbVar, a database of structural variation, the NCBI Variation Viewer, the NCBI Map Viewer, the Clone database and the NCBI Remap service. Dr. Church was also a founding member of the Genome Reference Consortium (GRC), an international group charged with improving the reference assembly for humans and other model organisms
Elinor Karlsson uses evolution as a tool for understanding how the human genome works. By combining signals of natural selection with genome-wide association studies, Dr. Karlsson aim to identify genes, pathways, and the functional variants underlying
polygenic diseases, and translate these discoveries into advances in human health care. She is currently using this approach to find the genetic risk factors for susceptibility to infectious diseases, like cholera and viral hemorrhagic fevers, as well as psychiatric disorders (using dogs as a model organism). Elinor received her B.A. in biochemistry/cell biology from Rice University, and earned her Ph.D. in bioinformatics from Boston University for research she did on dog genetics at the Broad Institute. She did her postdoctoral research with Dr. Pardis Sabeti at Harvard University.
Green Center for Systems Biology, University of Texas Southwestern Medical Center
Dr. Reynolds received her undergraduate training in biochemistry at Rice University. She completed her Ph.D. in biophysics with Dr. Tracy Handel at the University of California, Berkeley in 2006, where she studied the computational design of protein-protein interfaces. She then completed a postdoctoral fellowship in the lab of Dr. Rama Ranganathan at UT Southwestern, where she studied on the evolution and engineering of allosteric communication between proteins.
Pauline Ng has 15 years experience in bioinformatics and published over 30 publications with over 10,000 citations. Dr. Ng has developed applied health algorithms for predicting disease mutations such as SIFT.
She also designed the content for Illumina’s Infinium genotyping microarrays, which are used in the majority of genome-wide association studies. Dr. Ng was an Assistant Professor at J. Craig Venter Institute where she published the first sequenced individual human genome (Craig Venter’s) and critiqued personalized genetics companies such as 23andMe. She was a Group Leader ot Genome Institute of Singapore and CIO of its POLARIS program to establish the first CAP-certified NGS lab in Southeast Asia. Dr. Ng is currently an independent consultant.