Professor Ryan Lister completed his Bachelor’s degree in Biochemistry and Genetics at The University of Western Australia (UWA) in 2000, and undertook his Ph.D. studies in plant mitochondrial biogenesis at UWA from 2001-2005. After completing his PhD, Ryan was awarded a Human Frontiers Science Program Postdoctoral Fellowship in 2006 to undertake his postdoctoral studies in Joseph Ecker’s laboratory at The Salk Institute for Biological Studies in California, where his research focused on studying the epigenome, the molecular code superimposed upon the genome that plays important roles in regulating the information contained in the underlying DNA sequence. He developed new high-throughput DNA sequencing methodologies to profile the transcriptome and epigenome, including the first RNA-sequencing approach and whole genome bisulfite sequencing. This allowed, for the first time, the precise mapping of sites of DNA methylation throughout an entire genome. Ryan returned to Perth in 2012 to establish his own research group, and is currently a Sylvia and Charles Viertel Senior Medical Research Fellow and head of the Epigenetics and Genomics laboratory at the Harry Perkins Institute of Medical Research and UWA. His research has yielded new insights into the composition and function of the epigenome in a variety of systems, including the first integrated maps of the epigenome and transcriptome in a eukaryote, generation of the first human DNA methylomes, identification of epigenomic memory in human induced pluripotent stem cells, and discovery of widespread epigenome reconfiguration during brain development.