Professor James Hudson is the Group Leader of the Cardiac Bioengineering Research Group at QIMR Berghofer. James completed a Bachelor of Chemical and Biological Engineering (2006) followed by a PhD in Biotechnology (2011) at the University of Queensland. He then did a postdoc with Professor Wolfram-Hubertus Zimmermann in Göttingen, Germany.
James returned to Australia and became a group leader in 2014. James’ lab focusses on postnatal cardiac development and maturation. His lab has brought together engineering and cell biology disciplines to develop human cardiac organoid screening platforms and determine the molecular drivers of cardiac maturation. Drug discovery for heart failure is also a major focus of his lab and includes not only screening but in depth characterisation to determine mechanisms of action.
James is an inaugural recipient of the prestigious Snow Medical Fellowship (2021) and has won The Metcalf Prize for stem cell research (2019).
Professor Alicia Oshlack has been at the forefront of bioinformatics research for more than 15 years. She is the (co)Head of the Computational Biology Program and group leader at the Peter MacCallum Cancer Centre. She is best known for her large body of work on transcriptional analysis and medical genomics. In addition, Oshlack is internationally recognised for her development of bioinformatics methods for a range of applications including single cell RNA-seq, methylation and genomic analysis. Oshlack is involved in many cutting edge collaborative projects utilising high throughput sequencing to investigate disease and development. She has published more than 100 papers and has developed more than a dozen software packages. Oshlack has been recognised by several awards including the Australian Academy of Science, Gani Medal for Human Genetics (2011) and the Georgina Sweet Award for Women in Quantitative Biomedical research (2016).
Dr Zhong is a data scientist with background in computer science, applied statistics and cancer proteomics. He completed his undergraduate study in computer science and obtained a Doctor of Sciences degree in biochemistry and computer science at ETHZ (Swiss Federal Institute of Technology Zurich) in Switzerland. In 2017, he was recruited as the group leader for Cancer Data Science at Children’s Medical Research Institute and was subsequently appointed as a conjoint senior lecturer at the University of Sydney.
His group aims to collate and mine big biomedical data to achieve the goals of personalised medicine with a focus of developing data-driven, evidence-based computational tools and sophisticated machine learning algorithms to predict the most effective cancer treatments for individual patients. Related major research areas include proteogenomic data mining and management, genome-proteome association analysis and multi-omics data integration for large-scale cancer cohorts.
Alex is an internationally leading Aboriginal clinician/researcher who has worked his entire career in Aboriginal health in the provision of public health services, infectious diseases and chronic disease care, health care policy and research. Much of his work has been at the difficult interface of geographical isolation, complex cultural context, severe socioeconomic disadvantage, and profound health disparities.
His transdisciplinary program of research focuses on documenting the burden and contributors to health inequality in Indigenous Australians, with a primary focus on cardiovascular disease (CVD), diabetes and cancer, spanning time at Menzies School of Health Research, Baker IDI Heart and Diabetes Institute, and the South Australian Health and Medical Research Institute (2012-2021). During his most recent appointment at SAHMRI, he oversaw the establishment of an integrated centre of excellence in Indigenous chronic disease and public health research. In 2022 he will take up a new position as Professor of Indigenous Genomics for Telethon Kids Institute and ANU.
Stephen Leslie is Professor of Statistical Genomics at the University of Melbourne. Stephen completed his doctorate in statistics at the University of Oxford in 2008. After graduating, Stephen was a post-doctoral researcher in the Department of Statistics at Oxford and was then awarded one of Oxford’s prestigious Nuffield Department of Medicine Scientific Leadership Fellowships. In 2012 Stephen returned to Australia to establish his own research group. Since 2016 Stephen has been at the University of Melbourne, in the Schools of Mathematics and Statistics, and Biosciences, and Melbourne Integrative Genomics. In 2016 Stephen was awarded the Woodward Medal by the University of Melbourne, the University’s highest award for research by faculty. In 2019 Stephen was awarded the Moran Medal of the Australian Academy of Science.
Stephen’s work covers several aspects of statistical and population genetics. His main interests are in detecting, understanding and controlling for population differences in genetic data (including the landmark People of the British Isles study); typing complex genetic variation, with a particular focus on immune-associated loci (developed the first methods for typing variation in HLA and KIR from SNP genotype data; HLA typed the entire UK Biobank as part of the main data release); developing new statistical and computational approaches for analysing genomic data; and performing statistically rigorous analyses of the relationship of genetic variants to disease (many disease association studies with a particular focus on HLA and autoimmune disease).