Professor Matt Brown

Professor Matthew Brown, an internationally renowned clinician-scientist, joined Genomics England in 2021.

Prior to joining Genomics England he was Director of the National Institute for Health Research (NIHR) Guy’s and St Thomas’ Biomedical Research Centre and Professor of Medicine within the Faculty of Life Sciences and Medicine, King’s College London.

Professor Brown trained as a clinician-scientist and a rheumatologist, including a period of post-graduate study at the University of Oxford. He has made contributions to the development of gene-mapping approaches in human diseases and genome-wide association study methodology, leading to the discovery of thousands of genetic variants, with a particular interest in ankylosing spondylitis, rheumatoid arthritis and osteoporosis. In the genetics of rare human diseases, he has identified genes responsible for monogenic forms of arthritis, ectopic bone development, and skeletal dysplasias. He has also led efforts in Australia to translate research sequencing capability into precision medicine programs for cancer patients. His still practices medicine, in the specialty of rheumatology, with a particular focus on axial spondyloarthropathies.